南方医科大学基础医学院病理学系/南方医院病理科主任，广东省分子肿瘤病理实验室主任、国家二级教授/博士研究生导师，享受国务院政府津贴。国务院学位委员会学科评议组成员、国家级教学名师，国家优秀博士生论文指导教师。中国医师协会病理科医师分会会长、中华医学会病理学分会副主任委员、中国抗癌协会肿瘤转移专业委员会副主任委员、《诊断病理学杂志》副总编辑。《中华病理学杂志》、《中国肺癌杂志》、《中国肿瘤生物治疗杂志》、《南方医科大学学报》等杂志常务编委及编委。

长期从事结直肠癌转移分子机制研究， 主持及完成国家基金重点及面上项目、国家“863”课题、“973”分题、中德合作及省部级研究课题42项，发表SCI收录论文103篇（包括N Eng J Med 、Gastroenterology、Gut、Cell Res、Clin Cancer Res、J Pathol、Oncogene、J Proteomics Res等杂志），获广东省丁颖科技奖及国家级、省部级及中华医学会科技进步奖一、二等奖共9项。培养和招收博士后、博士及硕士研究生150余名（1人获国家杰出青年基金，2人获珠江学者，3人获国家优秀博士论文奖， 4人获广东省优秀博士论文奖）。

在结直肠癌转移机制研究方面形成了一定的特色和优势，成功地复制了化学药物诱导结直肠肠癌模型，建立了结直肠癌裸鼠皮下移植模型，肝转移模型，结直肠癌人羊膜基膜-血管内皮侵袭模型，定量化血管浸润模型，高浸润球体模型等系列新型模型，并较好地解决了肿瘤侵袭力的定量检测问题，采用微量培养连续选择分离技术，建立了国内首株人结直肠癌高浸润及高转移亚系，建立了原位RT-PCR间接法检测CD44V6mRNA病理学新技术，首次应用激光共焦三维重组分析技术，揭示了CD44V6与结直肠癌细胞骨架的关系，发现CD44V6主要通过改变结直肠癌细胞Actin构型和分布影响结直肠癌转移潜能，发现人结直肠癌细胞与人多器官的血管内皮细胞具有特异性粘附作用。阐明了癌细胞表面氨基多糖、CD44V6、P21、C-erbB-2可能是癌转移的分子标志物，较系统地揭示了结直肠癌血管侵袭与转移的形态学模式。利用cDNA微阵列技术已制备出结直肠癌转移相关基因芯片，较早开展肿瘤转移和肿瘤转移血清蛋白质组学研究，利用基因芯片及蛋白质组学技术筛选出结直肠癌转移相关候选基因29个，转移相关蛋白质16个，在癌基因的检测、扩增、克隆、测序、分子杂交、引物合成、肿瘤转移和肿瘤转移血清蛋白质组学研究等方面积累了丰富的经验。为肿瘤转移机制研究提供了丰富的研究资料。研究成果分别发表在J Pathol、Neoplasia、J Proteomics Research、 Int J Cancer、Modern  Pathol、Gut、Clin Cancer Res、Cell Res等杂志，在结直肠癌转移机制研究方面获国家及省部级科技进步二等奖共3项（署名均为第一、二）。

在SARS研究方面，主持完成国际前三例SARS尸解，提出SARS病理变化及SARS病毒在体内分布的全新概念，研究成果分别发表在国际著名杂志J Pathol（2003;200(3):282-289.IF=4.933；2004;203(2):622-630.， IF=5.333；2006;210(3):288-297，IF=5.983均为封面文章）, N Eng J Med（IF=38.57），分别被 SCI收录及SCI论文引用200余次，为SARS的防治作出了积极贡献，有较高的国际学术影响和良好的社会效益。SARS研究获广东省科技进步特等奖（病原组署名第一）、军队科技进步二等奖各1项（署名第一）及中华医学科技进步奖一等奖1项（署名第二）。

结直肠癌转移机制研究方的国家及省部级科技进步二等奖（7项）：

1、姜泊、丁彦青、李学农、周殿元、李祖国、张亚历、张振书、智发朝、孙青、肖冰  结直肠癌发生与转移分子调控及早期诊断的综合研究，国家科技进步二等奖 2004年

2、丁彦青、李学农、李祖国、邱红明、郭君其、蔡俊杰、邓永键、朱梅刚、张进华  结直肠癌转移的生物学特性及分子病理学研究，军队科技进步二等奖     1999年

3、丁彦青、姜泊、李祖国、李学农、周殿元、张亚历、张振书、孙青、智发朝    

结直肠癌早期诊治及发生与转移分子机制的系列研究，广东省科技进步二等奖  2003年

4、丁彦青、赵亮、梁莉、李建明、廖雯婷、王爽、李祖国、周军、邓永键、王晓燕 结直肠癌转移分子标志物的鉴定及分子机制研究  广东省科技一等奖（A04-0-1-02-R-01）2014年

5、丁彦青、赵亮、梁莉、廖雯婷、王爽、李祖国、周军、邓永键、王晓燕 结直肠癌转移分子标志物及分子机制  中华医学科技二等奖（201302232P0901）2013年

6、丁彦青、赵亮、梁莉、廖雯婷、王爽、李祖国、周军、邓永键、王晓燕 结直肠癌转移的分子标志物及分子机制   广州市科技一等奖（卫1-03-01）

教育经历

1970-09-01至1972-07-01解放军军医学院，临床医学，大学本科

1979-09-01至1981-07-01第一军医大学，临床医学，大学本科

1989-09-01至1991-07-01第一军医大学，肿瘤病理学，硕士研究生

工作经历

1993年-至今    第一军医大学/南方医科大学，病理学系主任

1989年-1992年第一军医大学副教授/副主任

1986年-1989年第一军医大学讲师/主治医师

1973年-1988年第一军医大学助教

作为项目负责人主持的国家级及省部级课题：

    1.2015-01-01至2020-12-31，国家重点基础研究发展计划（973计划，），CRC侵袭的早期分子事件及实验性靶向干预，项目组长（2015CB554002）。

2.2001-01-01至2006-12-31，国家高科技研究发展计划（863计划）项目，鼻咽癌药物筛选模型及基因治疗研究（2001AA216010）项目专题组长。

3.2013-01-01至2016-12-31，国家基金重点项目（NSFC-广东省联合基金），结直肠癌转移相关标志物的鉴定及分子机制和信号通路研究（U1201226）。

4.2014-01-01至2017-12-31，国家自然科学基金（81472313），利用肠道特异性FBX8条件敲除小鼠探讨FBX8在结直肠癌侵袭和转移中的作用机制。

5.2010-01-01至2013-12-31，国家自然科学基金(81071735)，叉头框基因FOXC2在结直肠癌转移中的作用及其分子机制

代表性著作及论文

1 Liang Zhao, Hui Wang, Chao Liu, Yawei Liu , Xiaoyan Wang, Shuang Wang , Xuegang Sun , Jianming Li , Yongjian Deng , Yong Jiang , Yanqing Ding.   Promotion of colorectal cancer growth and metastasis by the LIM and SH3 domain protein Gut. 2010.59(9)：1226-1235 (IF=10.712 通讯作者)

2 Wei-Jie Zhou, Zhen H Geng, Shan Chi, Wenli Zhang, Xiao-Feng Niu,     Shu-Jue Lan, Li Ma, Xuesong Yang, Li-Jing Wang, Yan-Qing Ding, Jian-Guo Geng, Slit-Robo signaling induces malignant transformation through Hakai-mediated E-cadherin degradation during colorectal epithelial cell carcinogenesis. Cell Research 2011 Apr;21(4):609-26  (IF=9.417  通讯作者)

3 Xi-ling Zhu, Yuan-feng Zeng, Jian Guan, Yu-fa Li, Yong-jian Deng,1 Xiu-wu Bian,6 Yan-qing Ding,and Li Liang. FMNL2 is a positive regulator of cell motility and metastasis in colorectal carcinoma. J Pathol 2011 Jul;224(3):377-88 (IF=7.274  通讯作者)

4 Qingling Z, Lina Y, Li L, Shuang W, Yufang Y, Yi D, Divakaran J, Xin L, Yanqing D. LMP1        antagonizes WNT/β-catenin signalling through inhibition of WTX and promotes nasopharyngeal dysplasia but not tumourigenesis in LMP1(B95-8) transgenic mice.  J Pathol. 2011 Apr;223(5):574-83  (IF=7.274  通讯作者)

5 Jin H, Li T, Ding Y, Deng Y, Zhang W, Yang H, Zhou J, Liu C, Lin J, Ding Y. Methylation status of T-lymphoma invasion and metastasis 1 promoter and its overexpression in colorectal cancer. Hum Pathol. 2011 Apr;42(4):541-51 (IF=3.266  通讯作者)

6 Hao JM, Chen JZ, Sui HM, Si-Ma XQ, Li GQ, Liu C, Li JL, Ding YQ, Li JM.  A five-gene signature as a potential predictor of metastasis and survival in colorectal cancer. J Pathol. 2010; 220: 475-489  (IF=7.274 通讯作者)

7 Zheng P, Liu YX, Chen L, Liu XH, Xiao ZQ, Zhao L, Li GQ, Zhou J, Ding YQ, Li JM. Stathmin, a New Target of PRL-3 Identified by Proteomic Methods, Plays a Key Role in Progression and Metastasis of Colorectal Cancer. J Proteome Res. 2010;9(10):4897-905 (IF=5.132  通讯作者)

8 Wang S, Li X, Li ZG, Lu J, Fan g WY, Ding YQ, Yao KT. Gene expression profile changes and possible molecular subtypes in differentiated-type nonkeratinizing nasopharyngeal carcinoma  Int J Cancer. 2011 Feb 15;128(4):753-62 (IF=4.734)

9 Li Y, Zhu X, Zeng Y, Wang J, Zhang X, Ding YQ, Liang L. FMNL2 enhances invasion of colorectal carcinoma by inducing epithelial mesenchymal transition. Mol Cancer Res. 2010 Dec;8(12):1579-90.（通讯作者，IF=4.533）

10 Li G, Liu C, Yuan J, Xiao X, Tang N, Hao J, Wang H, Bian X, Deng Y, Ding Y. CD133(+) single cell-derived progenies of colorectal cancer cell line SW480 with different invasive and metastatic potential. Clin Exp Metastasis. 2010 ;27;517-527  (IF=3.91  通讯作者)

11 .Liang L, Guan J, Wang JM, Zeng YF, Li XZ, Zhang XJ, Ding YQ. Down-regulation of FMNL2 predicts poor prognosis of hepatocellular carcinoma. Hum Pathol.. 2011 Nov;42(11):1603-12.（通讯作者IF=3.322）

12 Zhao L, Wang H, Sun X, Ding Y. Comparative proteomic analysis identifies proteins associated with the development and progression of colorectal carcinoma. FEBS J. 2010 Aug 31. [Epub ahead of print] (IF=3.042  通讯作者)

13 Meng HM, Zheng P, Wang XY, Liu C, Sui HM, Wu SJ, Zhou J, Ding YQ, Li JM. Overexpression of nanog predicts tumor progression and poor prognosis in colorectal cancer Cancer Biol Ther. 2010 Feb 16;9(4). [Epub ahead of print] (IF=2.873 通讯作者)

14 Li WZ, Wang XY, Li ZG, Zhang JH, Ding YQ. Celecoxib enhances the inhibitory effect of cisplatin on Tca8113 cells in human tongue squamous cell carcinoma in vivo and in vitro. J Oral Pathol Med. 2010；39:579--584 (IF=2.63通讯作者)

15 Liu QF, Fan ZP, Luo XD, Sun J, Zhang Y, Ding YQ. Epstein-Barr virus-associated pneumonia in patients with post-transplant lymphoproliferative disease after hematopoietic stem cell transplantation. Transpl Infect Dis. 2010 Mar 23. [Epub ahead of print]  (IF=2.516)

16 Zhao L, Liu Y, Sun X, He M, Ding Y. Overexpression of T lymphoma invasion and metastasis 1 predict renal cell carcinoma metastasis and overall patient survival. J Cancer Res Clin Oncol. 2010 Apr 29.  [Epub ahead of print] (IF=2.217通讯作者)

17 Hong-Jun Yang, Juan zhi Chen, Wen li Zhang, Yan-Qing Ding.  Focal adhesion plaque associated cytoskeletons are involved in the invasion and metastasis of human colorectal carcinoma. Cancer Invest. 2010;28(2):127-134. (IF =2.106 通讯作者)

18 Shuang Wang, Jun Zhou, Xiao-Yan Wang, Jun-Mei Hao, Juan-Zhi Chen, Xiang-Mei Zhang, He Jin, Li Liu, Yan-Fei Zhang, Jinsong Liu, Yan-Qing Ding, Jian-Ming Li  Down-regulated expression of SATB2 is associated with metastasis and poor prognosis in colorectal cancer  J Pathol 2009;219(1); 114-122 (IF=6.466 通讯作者)

19 Zhou J, Wang S, Lu J, Li J, Ding Y. Over-expression of phosphatase of regenerating liver-3 correlates with tumor progression and poor prognosis in nasopharyngeal carcinoma. Int J Cancer 2009;124(8):1879-1886. (通讯作者IF=4.734)

20 Ding Y, Chen B, Wang S, Zhao L, Chen J, Ding YQ, Chen L, Luo R. Overexpression of Tiam1 in hepatocellular carcinomas predicts poor prognosis of HCC patients. Int J Cancer 2009;124(3):653-658. (IF=4.734)

21 Liang zhao, Hui Wang , Yongjian Deng , Shuang Wang, Chao Liu , He jin , Yanqing Ding .Transgelin as a suppressor is associated with poor prognosis in colorectal carcinoma patients. Modern Patholgy 2009;22(6):786-796 （IF=4.286 通讯作者）

22 Yu hong Liu, Jun Zhou, Juanzhi Chen, Weizhe Gao, Yi Le, Yanqing Ding, Jianming Li. RL-3 promotes epithelial mesenchymal transition by regulating cadherin directly  Cancer Biol Ther. 2009;8(14):1352-1359 (IF=2.873 通讯作者)

23 Zhou J, Li J, Chen J, Liu Y, Gao W, Ding Y . Over-expression of CDH22 is associated with tumor progression in colorectal cancer. Tumour Biol. 2009;30(3):130-140. (IF=2.238 通讯作者)

24 Yang HJ, Ding YQ, Deng YJ. Multicentric reticulohistiocytosis with lungs and liver involved.  Clin Exp Dermatol  2009 ;34(2):183-185.

25 Qiu LW, Di B, Wen K, Wang XS, Liang WH, Wang YD, Pan YX, Wang M, Ding YQ, Che XY. Development of an antigen capture immunoassay based on monoclonal antibodies specific for dengue virus serotype 2 nonstructural protein 1 for early and rapid identification of dengue virus serotype 2 infections. Clin Vaccine Immunol 2009;16(1):88-95. (IF =1.995)

26 Zhao L, Wang H, Li J, Liu Y, Ding Y. Overexpression of Rho GDP-dissociation inhibitor alpha is associated with tumor progression and poor prognosis of colorectal cancer. J Proteome Res 2008;7(9):3994-4003. (IF=5.675  通讯作者)

27 Wu D, Ding Y, Wang S, Zhang Q, Liu L. Increased expression of high mobility group box 1 (HMGB1) is associated with progression and poor prognosis in human nasopharyngeal carcinoma. J Pathol 2008;216(2):167-175. (IF=5.556)

28 Sun G, Zhou J, Yin A, Ding Y, Zhong M. Silencing of ZNF217 gene influences the biological behavior of a human ovarian cancer cell line. Int J Oncol 2008;32(5):1065-1071. (IF=2.556通讯作者)

29 Zhu XL, Liang L, Ding YQ. Overexpression of FMNL2 is closely related to metastasis of colorectal cancer. Int J Colorectal Dis 2008;23(11):1041-1047. (IF=2.006  通讯作者)

30 Liao Q, Zhao L, Chen X, Deng Y, Ding Y. Serum proteome analysis for profiling protein markers associated with carcinogenesis and lymph node metastasis in nasopharyngeal carcinoma. Clin Exp Metastasis 2008;25(4):465-476. (IF=2.811 通讯作者)

31 Hao W, Pan YX, Ding YQ, Xiao S, Yin K, Wang YD, Qiu LW, Zhang QL, Woo PC, Lau SK, Yuen KY, Che XY. Well-characterized monoclonal antibodies against cell wall antigen of Aspergillus species improve immunoassay specificity and sensitivity. Clin Vaccine Immunol 2008;15(2):194-202. (IF=1.995)

32 Liu L, Wang S, Zhang Q, Ding Y. Identification of potential genes/proteins regulated by Tiam1 in colorectal cancer by microarray analysis and proteome analysis. Cell Biol Int 2008;32(10):1215-1222. (IF=1.363  通讯作者)

33 Liu T, Ding Y, Xie W, Li Z, Bai X, Li X, Fang W, Ren C, Wang S, Hoffman RM, Yao K. An imageable metastatic treatment model of nasopharyngeal carcinoma. Clin Cancer Res 2007;13(13):3960-3967. (IF=6.25)

34 Zhao L, Liu L, Wang S, Zhang YF, Yu L, Ding YQ. Differential proteomic analysis of human colorectal carcinoma cell lines metastasis-associated proteins. J Cancer Res Clin Oncol 2007;133(10):771-782. (IF=2.469通讯作者)

35 Liang L, Qu L, Ding Y. Protein and mRNA characterization in human colorectal carcinoma cell lines with different metastatic potentials. Cancer Invest 2007;25(6):427-434. (IF=2.335  通讯作者)

36 Liu L, Zhao L, Zhang Y, Zhang Q, Ding Y. Proteomic analysis of Tiam1-mediated metastasis in colorectal cancer. Cell Biol Int 2007;31(8):805-814. (IF=1.363 通讯作者)

37 Liu L, Zhang Q, Zhang Y, Wang S, Ding Y. Lentivirus-mediated silencing of Tiam1 gene influences multiple functions of a human colorectal cancer cell line. Neoplasia 2006;8(11):917-924. (IF=4.913 通讯作者)

38 Zhao L.Liu L,Ding Y Screening metastasis-associated proteins in colorectal cancer through proteome analysis. Progress in biochemistry and biophysics,2006;33(5):485-497. (IF=0.222  通讯作者)

39 Li XP, Li CY, Li X, Ding Y, Chan LL, Yang PH, Li G, Liu X, Lin JS, Wang J, He M, Kung HF, Lin MC, Peng Y. Inhibition of human nasopharyngeal carcinoma growth and metastasis in mice by adenovirus-associated virus-mediated expression of human endostatin. Mol Cancer Ther 2006;5(5):1290-1298. (IF=5.171)

40 Li X, Liu X, Li CY, Ding Y, Chau D, Li G, Kung HF, Lin MC, Peng Y. Recombinant adeno-associated virus mediated RNA interference inhibits metastasis of nasopharyngeal cancer cells in vivo and in vitro by suppression of Epstein-Barr virus encoded LMP-1. Int J Oncol 2006;29(3):595-603. (SCI，IF=6.25)

41 He L, Ding Y, Zhang Q, Che X, He Y, Shen H, Wang H, Li Z, Zhao L, Geng J, Deng Y, Yang L, Li J, Cai J, Qiu L, Wen K, Xu X, Jiang S. Expression of elevated levels of pro-inflammatory cytokines in SARS-CoV-infected ACE2+ cells in SARS patients: relation to the acute lung injury and pathogenesis of SARS. J Pathol 2006;210(3):288-297. (封面文章，IF=5.759 通讯作者)

42 Xu J, Zhong S, Liu J, Li L, Li Y, Wu X, Li Z, Deng P, Zhang J, Zhong N, Ding Y, Jiang Y. Detection of severe acute respiratory syndrome coronavirus in the brain: potential role of the chemokine mig in pathogenesis. Clin Infect Dis 2005;41(8):1089-1096. (IF=6.51)

43 Ding Y, He L, Zhang Q, Huang Z, Che X, Hou J, Wang H, Shen H, Qiu L, Li Z, Geng J, Cai J, Han H, Li X, Kang W, Weng D, Liang P, Jiang S. Organ distribution of severe acute respiratory syndrome (SARS) associated coronavirus (SARS-CoV) in SARS patients: implications for pathogenesis and virus transmission pathways. J Pathol 2004;203(2):622-630. （封面文章，IF=5.333 通讯作者)

44 Wang H, Ding Y, Li X, Yang L, Zhang W, Kang W. Fatal aspergillosis in a patient with SARS who was treated with corticosteroids. N Engl J Med 2003;349(5):507-508. (IF=34.833)

45 Liu L, Wu DH, Li ZG, Yang GZ, Ding YQ. Effects of KAI1/CD82 on biological behavior of human colorectal carcinoma cell line. World J Gastroenterol 2003;9(6):1231-1236. (IF=3.318   通讯作者)

46 Liu HX, Ding YQ, Li X, Yao KT. Investigation of Epstein-Barr virus in Chinese colorectal tumors. World J Gastroenterol 2003;9(11):2464-2468. (IF=3.318 通讯作者)

47 Li XN, Ding YQ, Liu GB. Transcriptional gene expression profiles of HGF/SF-met signaling pathway in colorectal carcinoma. World J Gastroenterol 2003;9(8):1734-1738. (IF=3.318)

48 Ding Y, Wang H, Shen H, Li Z, Geng J, Han H, Cai J, Li X, Kang W, Weng D, Lu Y, Wu D, He L, Yao K. The clinical pathology of severe acute respiratory syndrome (SARS): a report from China. J Pathol 2003;200(3):282-289. (封面文章，IF=4.933 通讯作者)

49 .Li XW, Ding YQ, Cai JJ, Yang SQ, An LB, Qiao DF. Studies on mechanism of Sialy Lewis-X antigen in liver metastases of human colorectal carcinoma. World J Gastroenterol 2001;7(3):425-430. (IF=1.445  通讯作者)

50 .Liao WT, Jiang D, Yuan J, Cui YM, Shi XW, Chen CM, Bian XW, Deng YJ, Ding Y. HOXB7     as prognostic factor and mediator of colorectal cancer progression Clin Cancer Res. 2011 Jun 1;17(11):3569-78 (IF=7.338 通讯作者)

51 Lin T, Ding YQ, Li JM  Overexpression of Nanog protein is associated with poor prognosis in gastric adenocarcinoma  Med Oncol. 2011 Feb 20. [Epub ahead of print] (IF=1.227通讯作者)

52  Xianzheng Li1,2, Jianmei Wang1,2, Xiaojing Zhang1,2, Yuanfeng Zeng1,2, Yanqing Ding1,2, and Li Liang1,2  Overexpression of RhoGDI2 Correlates with Tumor Progression and Poor Prognosis in Colorectal Carcinoma.  Ann Surg Oncol  DOI 10.1245/s10434-011-1944-4 (IF=4.182通讯作者)

53 Zhang X, Li N, Li X, Zhao W, Qiao Y, Liang L, Ding Y. Low expression of DAB2IP contributes to malignant development and poor prognosis in hepatocellular carcinoma.  J Gastroenterol Hepatol. 2011 Dec 14. doi: 10.1111/j.1440-1746.2011.07049.x. [Epub ahead of print] 通讯作者

54. Wang H, Huang H, Li W, Jin X, Zeng J, Liu Y, Gu Y, Sun X, Wen G, Ding Y, Zhao L. Nuclear localization of 14-3-3epsilon inversely correlates with poor long-term survival of patients with colorectal cancer.. J Surg Oncol. 2011 Nov 21. doi: 10.1002/jso.22152. [Epub ahead of print]  (IF=4.182通讯作者)

55. Liang L, Li X, Zhang X, Lv Z, He G, Zhao W, Ren X, Li Y, Bian X, Liao W, Liu W, Yang G, Ding Y..MicroRNA-137, a HMGA1 target, suppresses cell invasion and metastasis of colorectal carcinoma by directly targeting FMNL2. .Gastroenterology 2013 Mar;144(3):624-635. (IF=12.835通讯作者)

56. Liao WT, Li TT, Wang ZG, Wang SY, He MR, Ye YP, Qi L, Cui YM, Wu P, Jiao HL, Zhang C, Xie YJ, Wang JX, Ding YQ  microRNA-224 Promotes Cell Proliferation and Tumor Growth in Human Colorectal Cancer by Repressing PHLPP1 and PHLPP2

Clin Cancer Res. 2013：;19(17):4662-72  (IF=7.837通讯作者)

57. Wang F, Qiao Y, Yu J, Ren X, Wang J, Ding Y, Zhang X, Ma W, Ding Y, Liang L

FBX8 Acts as an Invasion and Metastasis Suppressor and Correlates with Poor Survival in Hepatocellular Carcinoma. PLoS One. 2013 Jun 27;8(6):e65495. Print 2013. PMID 23826080  [PubMed - as supplied by publisher]

58. Yu LN, Zhang QL, Li X, Hua X, Cui YM, Zhang NJ, Liao WT, Ding YQ  Tiam1 transgenic mice display increased tumor invasive and metastatic potential of colorectal cancer after 1,2-dimethylhydrazine treatment PLoS One. 2013 Sep 12;8(9):e73077. doi: 10.1371/journal.pone.0073077.  (IF=3. 73 通讯作者)

59. Liao WT, Liu JL, Wang ZG, Cui YM, Shi L, Li TT, Zhao XH, Chen XT, Ding YQ, Song LB   High expression level and nuclear localization of Sam68 are associated with progression and poor prognosis in colorectal cancer  BMC Gastroenterol. 2013 Aug 9;13(1):126. [Epub ahead of print]  (IF=2. 11)

60. Liao WT, Ye YP, Zhang NJ, Li TT, Wang SY, Cui YM, Qi L, Wu P, Jiao HL, Xie YJ, Zhang C, Wang JX, Ding YQ. MicroRNA-30b functions as a tumour suppressor in human colorectal cancer by targeting KRAS, PIK3CD and BCL2..  J Pathol. 2014 Mar;232(4):415-27. doi: 10.1002/path.4309（IF2012=7.585）通讯作者

61. Yang MH, Yu J, Chen N, Wang XY, Liu XY, Wang S, Ding YQ. Elevated MicroRNA-31 Expression Regulates Colorectal Cancer Progression by Repressing Its Target Gene SATB2. PLoS One. 2013 Dec 30;8(12):e85353. doi: 10.1371/journal.pone.0085353. 通讯作者

62. Lv Z, Zou H, Peng K, Wang J, Ding Y, Li Y, Ren X, Wang F, Chang R, Liang L, Ding Y. The Suppressive Role and Aberrent Promoter Methylation of BTG3 in the Progression of Hepatocellular Carcinoma. PLoS One. 2013 Oct 17;8(10):e77473. doi: 10.1371/journal.pone.0077473. 通讯作者

63．Yang M, Yu J, Jiang D, Li W, Wang S, Ding Y. microRNA-182 targets special AT-rich sequence-binding protein 2 to promote colorectal cancer proliferation and metastasis . Journal of Translational Medicine 2014, 12 :109 May 1;12:109. doi: 10.1186/1479-5876-12-109.  通讯作者

64.Wang H, An H, Wang B, Liao Q, Li W, Jin X, Cui S, Zhang Y, Ding Y, Zhao L. miR-133a represses tumour growth and metastasis in colorectal cancer by targeting LIM and SH3 protein 1 and inhibiting the MAPK pathway..

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65. Deng YJ, Tang N, Liu C, Zhang JY, An SL, Peng YL, Ma LL, Li GQ, Jiang Q, Hu CT, Wang YN, Liang YZ, Bian XW, Fang WG, Ding YQ.  CLIC4, ERp29 and Smac/DIABLO derived from metastatic cancer stem-like cells stratifies prognostic risks of colorectal cancer. Clin Cancer Res. 2014 Jul 15;20(14):3809-17 IF=7.837通讯作者

66． Wang H, Shi J, Luo Y, Liao Q, Niu Y, Zhang F, Shao Z, Ding Y, Zhao L.  LIM and SH3 protein 1 induces TGF-β-mediated epithelial-mesenchymal transition in human colorectal cancer by regulating S100A4 expression. Clin Cancer Res. 2014 Sep 24. pii: Clin Cancer Res.0485.2014. [Epub ahead of print]  IF=7.837

67.  Xu L, Zhang Y, Wang H, Zhang G, Ding Y, Zhao L. Tumor suppressor miR-1 restrains epithelial-mesenchymal transition and metastasis of colorectal carcinoma via the MAPK and PI3K/AKT pathway. J Transl Med. 2014 Sep 8;12(1):244. [Epub ahead of print]

68. Jiang HJ, Wang S, Ding Y. Emerging paradigms of long non-coding RNAs in gastrointestinal cancer. Am J Stem Cells. 2014 Sep 5;3(2):63-73. eCollection 2014. Review.

69. Guoyang He1,2,3*, Shuiwang Hu4*, Dan Zhang1,2, Pingxiang Wu1,2, Xiaohui Zhu1,2, Sainan Xin1,2, Guifeng Lu1,2, Li Liang1,2, Yanqing Ding1,2  FOXD3 is a tumor suppressor that affects growth, invasion, metastasis of hepatocellular carcinoma

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70. Y-M Cui1,2,3,6, H-L Jiao1,2,3,6, Y-P Ye1,2,3, C-M Chen1,2,3, J-X Wang1,2,3, N Tang1,2,3, T-T Li1,2,3, J Lin1,2,3, L Qi1,2,3, P Wu1,2,3, S-Y Wang1,2,3, M-R He4, L Liang1,2,3, X-W Bian5, W-T Liao1,2,3 and Y-Q Ding1,2,3 FOXC2 promotes colorectal cancer metastasis by directly targeting MET  Oncogene  . 2015 Aug 13;34(33):4379-90.  IF=8.559通讯作者

71．Cui YM, Jiang D, Zhang SH, Wu P, Ye YP, Chen CM, Tang N, Liang L, Li TT, Qi L, Wang SY, Jiao HL, Lin J, Ding YQ, Liao WT. FOXC2 promotes colorectal cancer proliferation through inhibition of FOXO3a and activation of MAPK and AKT signaling pathways. Cancer Lett. 2014 Oct 10;353(1):87-94.

72．Liao WT, Ye YP, Deng YJ, Bian XW, Ding YQ. Metastatic cancer stem cells: from the concept to therapeutics. Am J Stem Cells. 2014 Sep 5;3(2):46-62.

73.Wang S, Yang MH, Wang XY, Lin J, Ding YQ. Increased expression of miRNA-182 in colorectal carcinoma: an independent and tissue-specific prognostic factor. Int J Clin Exp Pathol. 2014 May 15;7(6):3498-503.

74. Lin J, Gu Y, Du R, Deng M, Lu Y, Ding Y. Detection of EGFR mutation in supernatant, cell pellets of pleural effusion and tumor tissues from non-small cell lung cancer patients by high resolution melting analysis and sequencing. Int J Clin Exp Pathol. 2014 Dec 1;7(12):8813-22.

75. Zhou W, He MR, Jiao HL, He LQ, Deng DL, Cai JJ, Xiao ZY, Ye YP, Ding YQ, Liao WT, Liu SD  The tumor-suppressor gene LZTS1 suppresses colorectal cancer proliferation through inhibition of the AKT-mTOR signaling pathway . Cancer Lett. 2015 Apr 28;360(1):68-75

76. Zhang QQ, Zhou DL, Lei Y, Zheng L, Chen SX, Gou HJ, Gu QL, He XD, Lan T, Qi CL, Li JC, Ding YQ, Qiao L, Wang LJ. Slit2/Robo1 signaling promotes intestinal tumorigenesis through Src-mediated activation of the Wnt/β-catenin pathway.. Oncotarget. 2015 Feb 20;6(5):3123-35.

77. Zhou ZH, Rao J, Wu F, Yang J, Tan J, Xu SL, Ding Y, Zhan N, Hu XG, Cui YH, Zhang X, Dong W, Liu XD, Bian XW. SEMA3F Prevents Metastasis of Colorectal Cancer by PI3K/Akt-dependent Down-Regulation of the ASCL2/CXCR4 Axis. J Pathol. 2015 Apr 10. doi: 10.1002/path.4541. [Epub ahead of print]

78. Wu P, Wang F, Wang Y, Men H, Zhu X, He G, Ma W, Xin S, Wu J, Liao W, Ding Y, He M, Liang L. Significance of FBX8 in progression of gastric cancer. Exp Mol Pathol. 2015 Mar 20;98(3):360-366.

79. Li Y, Lv Z, He G, Wang J, Zhang X, Lu G, Ren X, Wang F, Zhu X, Ding Y, Liao W, Ding Y, Liang L. The SOX17/miR-371-5p/SOX2 axis inhibits EMT, stem cell properties and metastasis in colorectal cancer. Oncotarget.  2015 Apr 20;6(11):9099-112.. [Epub ahead of print]

80. Ma W, Yu J, Qi X, Liang L, Zhang Y, Ding Y, Lin X, Li G, Ding Y. Radiation-induced microRNA-622 causes radioresistance in colorectal cancer cells by down-regulating Rb  Oncotarget.  2015 Jun 30;6(18):15984-94

81. He G, Hu S, Zhang D, Wu P, Zhu X, Xin S, Lu G, Liang L, Ding Y. Hypermethylation of FOXD3 suppresses cell proliferation, invasion and metastasis in hepatocellular carcinoma. Exp Mol Pathol. 2015 Jun 22 [Epub ahead of print]

82. Lu G, Sun Y, An S, Xin S, Ren X, Zhang D, Wu P, Liao W, Ding Y, Liang L. MicroRNA-34a targets FMNL2 and E2F5 and suppresses the progression of colorectal cancer. Exp Mol Pathol. 2015 Jun 20;99(1):173-179

83. Chang J, Lan T, Li C, Ji X, 83 Zheng L, Gou H, Ou Y, Wu T, Qi C, Zhang Q, Li J, Gu Q, Wen D, Cao L, Qiao L, Ding Y, Wang L. Activation of Slit2-Robo1 signaling promotes liver fibrosis.  J Hepatol. 2015 63 j 1413–1420．

84. Zeng Y, Xie H, Qiao Y, Wang J, Zhu X, He G, Li Y, Ren X, Wang F, Li L, Ding Y. FMNL2 regulates Rho/ROCK pathway to promote actin assembly and cell invasion of colorectal cancer. Cancer Sci. 2015 Aug 10. doi: 10.1111/cas.12768. [Epub ahead of print] PMID:

85．Wu Z, Yang H, Weng D, Ding Y. Rapid recurrence and bilateral lungs, multiple bone metastasis of malignant solitary fibrous tumor of the right occipital lobe: report of a case and review. Diagn Pathol. 2015 Jul 9;10:91. doi: 10.1186/s13000-015-0318-9. PMID:

86．Wang J, Zhu X, Hu J, He G, Li X, Wu P, Ren X, Wang F, Liao W, Liang L, Ding Y. The positive feedback between snail and DAB2IP regulates EMT, invasion and metastasis in colorectal cancer. Oncotarget. 2015 Aug 21. [Epub ahead of print]

87． Hu CT, Guo LL, Feng N, Zhang L, Zhou N, Ma LL, Shen L, Tong GH, Yan QW, Zhu SJ, Bian XW, Lai MD, Deng YJ, Ding YQ. MIF, secreted by human hepatic sinusoidal endothelial cells, promotes chemotaxis and outgrowth of colorectal cancer in liver prometastasis. Oncotarget. 2015 Sep 8;6(26):22410-23.

88. Gu Y, Wang Q, Guo K, Qin W, Liao W, Wang S, Ding Y, Lin J. TUSC3 promotes colorectal cancer progression and epithelial-mesenchymal transition (EMT) through WNT/β-catenin and MAPK signalling. J Pathol. 2016 May;239(1):60-71.

89. Chen N, Guo D, Xu Q, Yang M, Wang D, Peng M, Ding Y, Wang S, Zhou J.

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90. Li T, Lai Q, Wang S, Cai J, Xiao Z, Deng D, He L, Jiao H, Ye Y, Liang L, Ding Y, Liao W. MicroRNA-224 sustains Wnt/β-catenin signaling and promotes aggressive phenotype of colorectal cance. J Exp Clin Cancer Res. 2016 Jan 29;35:21. doi: 10.1186/s13046-016-0287-1.

91. Zhang F, Luo Y, Shao Z, Xu L, Liu X, Niu Y, Shi J, Sun X, Liu Y, Ding Y, Zhao L. MicroRNA-187, a downstream effector of TGFβ pathway, suppresses Smad-mediated epithelial-mesenchymal transition in colorectal cancer. Cancer Lett. 2016 Apr 10;373(2):203-13. doi: 10.1016/j.canlet.2016.01.037. Epub 2016 Jan 25.

92. Xu L, Wen G, Ding Y, Zhao L. A lethal mesenteric gastrointestinal stromal tumor: a case report and review of the literature. Int J Clin Exp Pathol. 2015 Sep 1;8(9):11715-21. eCollection 2015

93. Zheng L, Zhang Y, Lin S, Sun A, Chen R, Ding Y, Ding Y. Down-regualtion of miR-106b induces epithelial-mesenchymal transition but suppresses metastatic colonization by targeting Prrx1 in colorectal cancer. Int J Clin Exp Pathol. 2015 Sep 1;8(9):10534-44. eCollection 2015.

94. Xu X, Chang W, Yuan J, Han X, Tan X, Ding Y, Luo Y, Cai H, Liu Y, Gao X, Liu Q, Yu Y, Du Y, Wang H, Ma L, Wang J, Chen K, Ding Y, Fu C, Cao G. Periostin expression in intra-tumoral stromal cells is prognostic and predictive for colorectal carcinoma via creating a cancer-supportive niche. Oncotarget. 2016 Jan 5;7(1):798-813. doi: 10.18632/oncotarget.5985.

95. Wu Z, Yang H, Weng D, Ding Y. Rapid recurrence and bilateral lungs, multiple bone metastasis of malignant solitary fibrous tumor of the right occipital lobe: report of a case and review Diagn Pathol. 2015 Jul 9;10:91. doi: 10.1186/s13000-015-0318-9. Review.

96. Lu G, Sun Y, An S, Xin S, Ren X, Zhang D, Wu P, Liao W, Ding Y, Liang L. MicroRNA-34a targets FMNL2 and E2F5 and suppresses the progression of colorectal cancer. Exp Mol Pathol. 2015 Aug;99(1):173-9. doi: 10.1016/j.yexmp.2015.06.014. Epub 2015 Jun 20.

97. Li Y, Lv Z, He G, Wang J, Zhang X, Lu G, Ren X, Wang F, Zhu X, Ding Y, Liao W, Ding Y, Liang L. The SOX17/miR-371-5p/SOX2 axis inhibits EMT, stem cell properties and metastasis in colorectal cancer. Oncotarget. 2015 Apr 20;6(11):9099-112.

98. Zhou ZH, Rao J, Yang J, Wu F, Tan J, Xu SL, Ding Y, Zhan N, Hu XG, Cui YH, Zhang X, Dong W, Liu XD, Bian XW. SEMA3F prevents metastasis of colorectal cancer by PI3K-AKT-dependent down-regulation of the ASCL2-CXCR4 axis. J Pathol. 2015 Aug;236(4):467-78. doi: 10.1002/path.4541. Epub 2015 May 22.

99. Xie H, Ren X, Xin S, Lan X, Lu G, Y L, Ss Y, Zc Z, Wt L, Ding YQ, Liang L. Emerging roles of circRNA_001569 targeting miR-145 in the proliferation and invasion of colorectal cancer. Oncotarget. 2016 Apr 5. doi: 10.18632/oncotarget.8589. [Epub ahead of print]

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发明专利：

1.赵亮、丁彦青，一种石蜡包埋组织提取蛋白质的方法，国家发明专利、2008年，中国；

2.邓永键、丁彦青、马丽丽，细胞侵袭趋化模型及其制备方法，国家发明专利，2016年，中国。