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Andrew Morris 博士

发布机构:深圳市人民医院  发布时间:2017-06-01

    Professor Andrew Morris 博士

    职 称: 正高/教授  

    深圳市三名工程团队:英国爱丁堡大学Andrew Morries教授糖尿病研究团队

    电 话: +86-755-25533018

    传 真: +86-755-25504575

    Email: 

    个人简历

    学术成果简介

    Andrew Morris教授是爱丁堡大学医学教授。自2014年8月至今,他担任人口健康科学及信息学Usher研究所所长,并任爱丁堡大学副校长(分管数据科学)。在此之前,他曾任邓迪大学医学系主任。Andrew Morris教授兼任苏格兰政府健康部首席科学家,该部门致力于支持并促进提高苏格兰NHS服务质量和成本效益方面的高质量研究,以确保持续改善苏格兰人民的健康状况。Andrew Morris教授的研究领域涵盖了信息学和慢性病研究。他是苏格兰法尔研究所主任(Farr Institute),该研究所受到英国医学研究理事会(MRC)以及其他九个机构的资金支持。同时,他也是英国健康信息学研究网络的召集人,使该网络获得了三千九百万英镑的健康信息学研究注资。Andrew Morris教授的研究兴趣在于运用信息学研究流行病和糖尿病的分子病原基础及其复杂性。他曾经发表了三百余篇原创性论文,并吸引了五千多万英镑的研究资金支持。同时,他还担任惠康基金会(Wellcome Trust)英国2型糖尿病病例控制收集的首席调查员,该病例调查招募了两万名病人参与。此外,他也担任该基金会一项名为“Generation Scotland”研究项目的首席调查员,对五万名苏格兰人的基因健康状况进行了研究,还领导了该基金会资助的苏格兰健康信息研究项目(SHIP).2003年,Andrew Morris教授荣获英国糖尿病研究劳伦斯奖( RD Lawrence Award by Diabetes UK);2013年荣获阿诺德布鲁姆讲座奖;2005年荣获十字协会苏格兰科学奖。此外,他是爱丁堡皇家学会会员、苏格兰科学与文学国家学会会员以及英国医学科学院会员。2007年,他与他人合作创立了Aridhia信息公司(Aridhia Informatics)。该公司现在苏格兰有70余名员工,在医疗健康领域应用高性能计算与分析,其业务已覆盖英国、中东以及澳大利亚西亚等地。Andrew Morris教授现任健康基金会主席,该基金会是英国最重要的慈善机构致力于推进医疗健康的质量。此外,他还是伦敦大学学院信息学委员会主席。2017年8月1日起Andrew Morris教授将担任英国国家健康与生物医学信息研究学会的卫生数据研究主席。

     

     

    主持项目:

    1.discover Edinburgh Health Informatics                 Morris, A.

    1/03/16 → 31/08/17£187,500, MRC

    Project: Research

    2.Trusted Data Safe Havens for Healthcare                Elliot, E., Morris, A. & Robertson, D.

    1/01/16 → 31/12/16£288,477, EU government bodies

    Project: Research

    3.RA3075 i2Health - Indistrial Innovation in Healthcare      Morris, A.

    1/03/15 → 31/08/16£244,122, MRC

    Project: Research

    4.UK Health Informatics Research Network               Morris, A.

    18/08/14 → 31/10/18£64,079, MRC

    Project: Research

    5.UK Health Informatics Research Network               Morris, A.

    18/08/14 → 31/10/18£1,267,741, MRC

    Project: Research

    6.UK Health Informatics Research Network               Morris, A.

    18/08/14 → 31/10/18£850,622, MRC

    Project: Research

    7.Administrative Data Research Centre - Scotland           Morris, A.

    1/11/13 → 31/10/18£23,596, ESRC

    Project: Research

    8.MRC: The Scottish eHealth Informatics Research Centre    Morris, A.

    1/03/13 → 28/02/18£61,112, Other

    Project: Research

     

    代表性著作及论文

    1.Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

    Navarro, P. , Vitart, V. , Campbell, H. , Hastie, N. D. , Porteous, D. J. , Rudan, I. , Wild, S. , Wright, A. F. , Hayward, C. , Morris, A. P. , Polasek, O. , Wilson, J. F. & 305 others 26 Apr 2017 In : Nature Communications. 8, p. 14977

     

    2.Discovery of novel heart rate-associated loci using the Exome Chip

    Morris, A. D. , Porteous, D. J. , Rudan, I. , Hayward, C. & 117 others 3 Apr 2017 In : Human Molecular Genetics.

     

    3.Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants

    Boutin, T. S. , Kerr, S. M. , Campbell, A. , Amador, C. , Howard, D. M. , Navarro, P. , Morris, A. , Deary, I. J. , Joshi, P. , Wilson, J. F. , Hastie, N. D. , Wright, A. F. , McIntosh, A. M. , Porteous, D. J. , Haley, C. S. , Vitart, V. , Hayward, C. & 8 others 7 Mar 2017 In : Genome Medicine. 9, 1, p. 23

     

    4.Rare and low-frequency coding variants alter human adult height

    Deary, I. J. , Hayward, C. , Mitchell, P. , Morris, A. D. , Pirie, A. , Polasek, O. , Rudan, I. , Starr, J. M. , Vitart, V. & 363 others 9 Feb 2017 In : Nature. 542, 7640, p. 186-190

     

    5.Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

    Campbell, A. , Porteous, D. J. , Wilson, J. F. , Joshi, P. K. , Deary, I. J. , Harris, S. E. , Rudan, I. , Kerr, S. M. , Polasek, O. , Vitart, V. , Hayward, C. , Morris, A. P. & 95 others 6 Feb 2017 In : Nature Genetics.

     

    6.A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

    Hayward, C. , Wild, S. H. , Campbell, H. , Hastie, N. , Morris, A. P. , Vitart, V. , Wright, A. F. , Rudan, I. , Wilson, J. F. & 267 others 23 Nov 2016 In : Nature Communications. 7, p. 13357

     

    7.Healthcare Data Safe Havens: Towards a Logical Architecture and Experiment Automation

    Robertson, D., Giunchiglia, F., Pavis, S., Turra, E., Bella, . G., Elliot, E., Morris, A., Atkinson, M., McAllister, G., Manataki, A., Papapanagiotou, P. & Parsons, M. 19 Oct 2016 In : The Journal of Engineering. 24 p.

     

    8.Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

    Harris, S. E. , Marioni, R. , Polasek, O. , Rudan, I. , Deary, I. J. , Starr, J. M. , Morris, A. D. , Porteous, D. J. , Hayward, C. & 202 others 12 Sep 2016 In : Nature Genetics.

     

    9.Identifying risk factors for progression to critical care admission and death among individuals with acute pancreatitis: a record linkage analysis of Scottish healthcare databases

    Mole, D. J., Gungabissoon, U., Johnston, P., Cochrane, L., Hopkins, L., Wyper, G. M. A., Skouras, C., Dibben, C., Sullivan, F., Morris, A., Ward, H. J. T., Lawton, A. M. & Donnan, P. T. 15 Jun 2016 In : BMJ Open. 6, 6

     

    10.Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

    Morris, A. D. & 128 others 24 Mar 2016 In : The New England Journal of Medicine. 374, 12, p. 1134-1144 11 p.

     

    11.Timing, rates and spectra of human germline mutation

    Rahbari, R., Wuster, A., Lindsay, S. J., Hardwick, R. J., Alexandrov, L. B., Al Turki, S., Dominiczak, A., Morris, A., Porteous, D., Smith, B., Stratton, M. R., Hurles, M. E. & UK10K Consortium 14 Dec 2015 In : Nature Genetics.

     

    12.Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

    Joshi, P. K. , Polasek, O. , Campbell, H. , Harris, S. E. , Navarro, P. , Starr, J. M. , Wild, S. H. , Wright, A. F. , Vitart, V. , Rudan, I. , Deary, I. J. , Wilson, J. F. , Morris, A. P. , Hayward, C. & 77 others 4 Dec 2015 In : Nature Communications. 6, p. 8658

     

    13.Epidemiology and Heritability of Major Depressive Disorder, Stratified by Age of Onset, Sex, and Illness Course in Generation Scotland: Scottish Family Health Study (GS:SFHS)

    Fernandez-Pujals, A. M., Adams, M. J., Thomson, P., McKechanie, A. G., Blackwood, D. H. R., Smith, B. H., Dominiczak, A. F., Morris, A. D., Matthews, K., Campbell, A., Linksted, P., Haley, C. S., Deary, I. J., Porteous, D. J., MacIntyre, D. J. & McIntosh, A. M. 16 Nov 2015 In : PLoS One. 10, 11, p. e0142197

     

    14.Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

    Morris, A. D. & 217 others 9 Nov 2015 In : Nature Genetics. 47, 12, p. 1415-25 11 p.

     

    15.Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): A genetic association study in UK Biobank

    Morris, A. P. , Wilson, J. F. , Wild, S. H. , Campbell, H. , Rudan, I. , Polasek, O. , Vitart, V. , Hayward, C. , Wright, A. F. , Satsangi, J. & 148 others 1 Oct 2015 In : The Lancet Respiratory Medicine. 3, 10, p. 769-781 13 p.

     

    16.The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

    Wild, S. H. , Wilson, J. F. , Campbell, H. , Hastie, N. , Morris, A. P. , Wright, A. F. , Hayward, C. , Rudan, I. , Vitart, V. & 431 others Oct 2015 In : PLoS Genetics. 11, 10, p. e1005378

    17.Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

    Morris, A. P. & 41 others Sep 2015 In : Nature Genetics. 47, 9, p. 979-86 8 p.

     

    18.A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough

    Morris, A. D. & 46 others 14 Jul 2015 In : Pharmacogenomics Journal.

     

    19.Directional dominance on stature and cognition in diverse human populations

    Joshi, P. K. , Vitart, V. , Campbell, A. , Haley, C. , Harris, S. E. , Hastie, N. D. , Kerr, S. M. , Navarro, P. , Wild, S. , Morris, A. D. , Morris, A. P. , Starr, J. M. , Deary, I. J. , Pirastu, N. , Wilson, J. G. , Rudan, I. , Porteous, D. J. , Hayward, C. , Wright, A. F. , Campbell, H. & 340 others 1 Jul 2015 In : Nature. 523, 7561, p. 459-462

     

    20.Copy number variation in the human Y chromosome in the UK population

    Wei, W., Fitzgerald, T. W., Ayub, Q., Massaia, A., Smith, B. H., Dominiczak, A. F., Morris, A. D., Porteous, D. D., Hurles, M. E., Tyler-Smith, C. & Xue, Y. Jul 2015 In : Human Genetics. 134, 7, p. 789-800 12 p.

     

    21.Mosaic structural variation in children with developmental disorders

    Morris, A. D. , Porteous, D. J. & 27 others 15 May 2015 In : Human Molecular Genetics. 24, 10, p. 2733-45 13 p.

     

    22.Genetic studies of body mass index yield new insights for obesity biology

    Bolton, J. L. , Fraser, R. M. , Hayward, C. , McLachlan, S. , Campbell, H. , Morris, A. D. , Price, J. F. , Rudan, I. , Walker, M. , Wilson, J. F. , Visscher, P. M. & 485 others 12 Feb 2015 In : Nature. 518, 7538, p. 197-U401 23 p.

     

    23.New genetic loci link adipose and insulin biology to body fat distribution

    Hayward, C. , Campbell, H. , Morris, A. D. , Rudan, I. , Wilson, J. F. , Walker, M. , Visscher, P. M. & 412 others 12 Feb 2015 In : Nature. 518, 7538, p. 187-U378 22 p.

     

     

    24.Estimated Life Expectancy in a Scottish Cohort With Type 1 Diabetes, 2008-2010

    Livingstone, S. J., Levin, D., Looker, H. C., Lindsay, R. S., Wild, S. H., Joss, N., Leese, G., Leslie, P., McCrimmon, R. J., Metcalfe, W., McKnight, J. A., Morris, A. D., Pearson, D. W. M., Petrie, J. R., Philip, S., Sattar, N. A., Traynor, J. P., Colhoun, H. M., Scottish Diabet Res Network Epidem & Scottish Renal Registry 6 Jan 2015 In : JAMA: the Journal of the American Medical Association. 313, 1, p. 37-44 8 p.

     

    25.Diagnostic accuracy of pulmonary host inflammatory mediators in the exclusion of ventilator-acquired pneumonia

    Morris, A. C. , Walsh, T. S. , Anderson, N. H. & 27 others Jan 2015 In : Thorax. 70, 1, p. 41-47 7 p.

     

    26.Metformin in cancer treatment and prevention

    Morales, D. R. & Morris, A. D. 2015 In : Annual Review of Medicine. 66, p. 17-29 13 p.

     

     

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