彭松林
发布机构：深圳市人民医院 发布时间：2023-07-05
彭松林
职称：主任医师、教授
专长：脊柱常见疾病的诊断和治疗（擅长脊柱退变疾病、畸形、肿瘤和骨折的手术）；骨质疏松症基础和临床
研究方向：
1、骨质疏松症的发病机制及骨折防治策略
2、椎间盘稳态的机制及修复的新策略
个人简历
获得临床医学（华中科技大学）和科研医学（香港大学）双博士学位，深圳市人民医院（南方科技大学和暨南大学附属医院）主任医师，研究生导师及博士后合作导师，深圳市骨科研究所副所长，深圳市海外高层次人才。2009年和2017年分别在美国哥伦比亚大学及南加州大学脊柱中心进修学习。熟练掌握脊柱外科的常规手术技术，擅长以下疾病的治疗：
1）脊柱退变：如脊髓型颈椎病、神经根型颈椎病、颈椎管狭窄症、颈椎后纵韧带骨化症、胸椎黄韧带骨化症、腰椎滑脱症、腰椎管狭窄症、腰椎间盘突出症等的微创和精准手术;
2）脊柱畸形：如青少年特发性脊柱侧弯及老年人退变性脊柱侧弯的矫形手术；
3）脊柱骨折：如爆裂性骨折或骨质疏松压缩性骨折的复位内固定或骨水泥微创手术；脊柱骨折并发的截瘫或不全瘫减压及重建手术；
4）脊柱感染：如脊柱结核或化脓性感染的病灶清除手术；采用脊柱微创（如椎间孔镜技术）完成感染性病灶的清除；脊柱结核手术的病例科研成果发表在临床医学四大顶级期刊之一的《英国医学杂志》（BMJ）；
5）脊柱肿瘤：如脊柱转移瘤、椎管内肿瘤的切除和重建手术
彭医生以医者仁心的态度，为每一位前来就诊的患者提供最佳的治疗方案，为每一位手术患者提供最精准的方案，提供贴心和周到的围手术期安排，受到医院内同行及社会各界的认可，在健康160上患者及家属好评如潮。彭医生长期潜心骨质疏松及骨修复领域临床和科研工作，定期组织各种骨质疏松症健康宣教和社区义诊活动，为老年人提供专业的咨询和指导，受到良好的社会效应。对于骨质疏松骨折及老年脊柱融合手术患者，术后强调抗骨质疏松治疗并加强随访调查。在医院高水平医院登峰计划资助下，组建了大骨科专职科研人员团队并组建专门骨科基础研究的实验室，2021年获得“深圳市运动系统组织与功能重建重点实验室”，并担任重点实验室负责人。近10年来，彭医生主持国家级、省市级科研项目15项，其中包括国家自然科学基金面上项目2项，瑞士国家基金1项，广东省自然科学基金3项，深圳市科技创新委基金9项。发表SCI论文63篇，以第一或通讯作者发表SCI论文34篇，其中影响因子大于10分论文14篇,包括Bone Research, Nature Communications, Biomaterials等著名期刊。获得国家发明专利8项。担任Bone杂志编委，是中华医学会骨科分会基础学组青年委员及中国医师协会骨科分会颈椎学组青年委员。作为研究生及博士后导师，培养博士后5名，博士生1名，硕士生3名。
联系方式：电 话： +86-15099949091
Email： pengsonglin@mail.sustech.edu.cn
工作简历：
1997-2002 三峡大学， 医学学士
2002-2005 华中科技大学， 医学硕士（骨科）
2005-2008 华中科技大学，医学博士 （骨科）
2008-2011 香港大学， 科研医学博士（骨科）
2011-2016 深圳市人民医院， 主治医师
2016-2022 深圳市人民医院，副主任医师，副教授
2022-至今 深圳市人民医院，主任医师，教授，骨科研究所副所长
代表性论文
(*代表并列第一作者，#代表通讯作者)
Publications as corresponding authors or first (co-first) authors (n=35)
1. Wang H, Peng S#. A Pott diagnosis. BMJ 2023;381:e073764 (IF: 93)
2. Xie Y, Bao Z, Wang Z, Du D, Chen G, Liu C, Wang H, Feng N, Xiao X, Wang S, Zhang X, Zhu Y, Yuan Z, Long H#, Yang D#, Peng S#. Magnesium ascorbyl phosphate promotes bone formation via CaMKII signaling. J Bone Miner Res. 2023 May 2. doi: 10.1002/jbmr.4820. (IF: 6.390)
3. Lyu FJ, Peng S, Li J. Editorial: Progress on musculoskeletal disorders and stem cell therapies. Front Bioeng Biotechnol. 2023 Feb 23;11:1153525. (IF: 6.06)
4. Chen Z, Huai Y, Chen G, Liu S, Zhang Y, Li D, Zhao F, Chen X, Mao W, Wang X, Yin C, Yang C, Xu X, Ru K, Deng X, Hu L, Li Y, Peng S#, Zhang G#, Lin X#, Qian A#. MiR-138-5p Targets MACF1 to Aggravate Aging-related Bone Loss. Int J Biol Sci. 2022 Jul 18;18(13):4837-4852. (IF: 10.750)
5. Chen G, Long C, Wang S, Wang Z, Chen X, Tang W, He X, Bao Z, Tan B, Zhao J, Xie Y, Li Z, Yang D#, Xiao G#, Peng S#. Circular RNA circStag1 promotes bone regeneration by interacting with HuR. Bone Res. 2022 Mar 31;10(1):32. doi: 10.1038/s41413-022-00208-x. (IF: 13.362)
6. Liu Y#, Zhou T, Wang Q, Fu R, Zhang Z, Chen N, Li Z, Gao G#, Peng S#, Yang D#. m6 A demethylase ALKBH5 drives denervation-induced muscle atrophy by targeting HDAC4 to activate FoxO3 signalling. J Cachexia Sarcopenia Muscle. 2022 Apr;13(2):1210-1223. (IF: 12.063)
7. Chen X*, Tan B*, Bao Z*, Wang S, Tang R, Wang Z, Chen G, Chen S, Lu WW, Yang D#, Peng S#. Enhanced bone regeneration via spatiotemporal and controlled delivery of a genetically engineered BMP-2 in a composite Hydrogel. Biomaterials. 2021 Sep 2;277:121117. doi: 10.1016/j.biomaterials.2021.121117. (IF: 15.304)
8. Chen X, Tan B, Wang S, Tang R, Bao Z, Chen G, Chen S, Tang W, Wang Z, Long C, Lu WW, Yang D#, Bian L#, Peng S#. Rationally designed protein cross-linked hydrogel for bone regeneration via synergistic release of magnesium and zinc ions. Biomaterials. 2021 May 12; 274: 120895. doi: 10.1016/j.biomaterials.2021.120895. (IF: 15.304)
9. Wang Z, Zhao J, Tang WJ, Hu LQ, Zou T, Wang JH, Zhou RH, Yang DZ#, Peng S#. Multifunctional Nanoengineered Hydrogels Consisting of Black Phosphorus Nanosheets Up-Regulate Bone Formation. Small, 2019, 2019 Oct;15(41):e1901560. (IF: 15.153)
10. Chen Z, Zhao F, Liang C, Hu L, Li D, Zhang Y,Yin C, Chen L, Wang L, Lin X, Su P, Ma J, Yang C, Tian Y, Zhang W, Li Y, Peng S#, Chen W#, Zhang G#, Qian A#. Silencing of miR-138-5p sensitizes bone anabolic action to mechanical stimuli. Theranostics, 2020; 10(26): 12263-12278. (IF: 11.6)
11. Chen Y, Li C, Wang Z, Long J, Wang R, Zhao J, Tang W, Zhao Y, Qin L, Peng S#, Lai Y#. Self-assembled nanocomposite hydrogels enhanced by nanoparticles phosphonate-magnesium coordination for bone regeneration. Applied Materials Today 2021 Dec doi.org/10.1016/j.apmt.2021.101182. (IF: 10.041)
12. Wang ZM, Wang ZF, Zhen WX, Yang DZ#, Peng S#. Novel Biomaterial Strategies for Controlled Growth Factor Delivery for Biomedical Applications. NPG Asia Materials (2017) 9, e435; doi:10.1038/am.2017.171 (IF: 10.761)
13. Liang C*, Peng S* (Co-first author), Li J, et al. Inhibition of osteoblastic Smurf1 promotes bone formation in mouse models of distinctive age-related osteoporosis. Nature Communications, 2018 Aug 24;9(1):3428. doi: 10.1038/s41467-018-05974-z. (IF: 17.694)
14. Wang Z*, He X*, He T, Zhao J, Wang S, Peng S#, Yang D#, Ye L#. Polymer Network Editing of Elastomers for Robust Underwater Adhesion and Tough Bonding to Diverse Surfaces. ACS Appl Mater Interfaces. 2021 Aug 4;13(30):36527-36537. (IF: 10.383)
15. Wang Z, Zhao J, Tang W, He T, Wang S, He X, Chen Y#, Yang D#, Peng S#. Robust Underwater Adhesives Based on Dynamic Hydrophilic and Hydrophobic Moieties to Diverse Surfaces. ACS Appl Mater Interfaces. 2021 Jan 20;13(2):3435-3444. (IF: 10.383)
16. Chen G*, Wang S*, Long C, Wang Z, Chen X, Tang W, He X, Bao Z, Tan B, Lu William W, Li Z#, Yang D#, Xiao G#, Peng S#. PiRNA-63049 inhibits bone formation through Wnt/β-catenin signaling pathway. Int J Biol Sci. 2021Oct 25; 17(15): 4409-4425. (IF: 10.750)
17. Chen G, Tang W, Wang S, Long C, He X, Yang D, Peng S#. Promising diagnostic and therapeutic circRNAs for skeletal and chondral disorders. Int J Biol Sci. 2021 Apr 7;17(5) :1428-1439. (IF: 10.750)
18. Sun M, Hu L, Wang S, Huang TL, Zhang M, Yang M, Zhen W, Yang DZ, Lu WW, Guan M#, Peng S#. MicroRNA-19b Identified from Osteoporotic Vertebral Compression Fracture Patients Increases Bone Formation. J Bone Miner Res, 2020 Feb;35(2):306-316. (IF: 6.390)
19. Zhao H, Wang Q, Hu L, Xing S, Gong H, Liu Z, Qin P, Xu J, Du J, Ai W, Peng S#, Li Y#. Dynamic Alteration of the Gut Microbiota Associated with Obesity and Intestinal Inflammation in Ovariectomy C57BL/6 Mice. Int J Endocrinol 2022 Jan 22;2022:6600158.doi: 10.1155/2022/6600158.
20. Xiao X, Chen G, Wang S, Liu J, Lin E, Chen K, Xiang Y, Zhan K, Liu C, Yuan Z, Yang M, Zhong S, Zhen W, Yang D, Peng S#. Efficacy of the Dynesys Hybrid Surgery for Patients with Multi-Segmental Lumbar Spinal Stenosis. Front Surg. 2022 May 26;9:849679. (IF: 2.568)
21. Yao Z, Li L, Zhang P, Yang L, Bai X, Peng S#, Lai Y#. Biomechanics evaluation of sacroiliac joint pain after lumbosacral fusion: A finite element analysis. J Orthop Res. 2022 Jul 3. doi: 10.1002/jor.25411. (IF: 3.102)
22. Liu Y, Wang Q, Zhang Z, Fu R, Zhou T, Long C, He T, Yang D#, Li Z#, Peng S#. Magnesium supplementation enhances mTOR signalling to facilitate myogenic differentiation and improve aged muscle performance. Bone. 2021 May;146:115886. doi: 10.1016/j.bone.2021.115886. (IF: 4.626)
23. Sun T, Li Z, Zhong X, Cai Z, Ning Z, Hou T, Xiong L, Feng Y, Leung F#, Lu WW#, Peng S#. Strontium inhibits osteoclastogenesis by enhancing LRP6 and β-catenin-mediated OPG targeted by miR-181d-5p. J Cell Commun Signal. 2019 Mar;13(1):85-97. (IF: 5.908)
24. Wang Z, Wang D, Yang D, et al, Peng S#. The Effect of Icariin on bone metabolism and its potential clinical applications. Osteoporos Int (2017). https://doi.org/10.1007/s00198-017-4255-1. (IF: 5.071)
25. Sun T, Li CT, Xiong L, Ning Z, Leung F#, Peng S#, Lu WW#. miR-375-3p negatively regulates osteogenesis by targeting and decreasing the expression levels of LRP5 and β-catenin. PLoS One. 2017 Feb 3;12(2):e0171281. doi: 10.1371/journal.pone.0171281. (IF: 3.240)
26. Sun M, Zhou X, Chen L, Huang S, Leung V, Wu N, Pan H, Zhen W, Lu W, Peng S#. The Regulatory Roles of MicroRNAs in Bone Remodeling and Perspectives as Biomarkers in Osteoporosis. Biomed Res Int. 2016;2016:1652417. doi: 10.1155/2016/1652417. (IF: 3.05)
27. Zhou X, Chen L, Grad S, et al. Peng S#. The roles and perspectives of microRNAs as biomarkers for intervertebral disc degeneration. J Tissue Eng Regen Med. 2017 Dec;11(12):3481-3487. (IF: 4.323)
28. Peng S*, Liu XS, Huang S, Pan H, Zhen W, Zhou G, Luk KD, Guo XE, Lu WW. Intervention Timing of Strontium Treatment on Estrogen Depletion-Induced Osteoporosis in Rats: Bone Microstructure and Mechanics. J Orthop Res, 2014 Mar;32(3):477-84. (IF: 3.102)
29. Peng S*, Zhang G, Zhang BT, Guo B, He Y, Bakker AJ, Pan X, Zhen W, Hung L, Qin L, Leung WN. The Beneficial Effect of Icaritin on Osteoporotic Bone is Dependent on the Treatment Initiation Timing in Adult Ovariectomized Rats. Bone 2013; 55(1):230-40. (IF: 4.626)
30. Peng S*, Zhen W, Lu WW. Osteoprotegerin plays a key role in the dual action of strontium on bone remodeling: Evidences from bench to clinic. Bone 2012, 50:1203-1204. (IF: 4.626)
31. Peng S*, Liu XS*, Huang S, Li Z, Pan H, Zhen W, Luk KD, Guo XE, Lu WW. The Cross-talk Between Osteoclasts and Osteoblasts in Response to Strontium Treatment: Involvement of Osteoprotegerin. Bone 2011 Dec;49(6):1290-8. (IF: 4.626)
32. Peng S*, Liu XS, Zhou G, Li Z, Luk KD, Guo XE, Lu WW. Osteoprogeterin deficiency attenuates strontium-mediated inhibition of osteoclastogenesis and bone resorption J Bone Miner Res 2011 Jun;26(6):1272-82. (IF: 6.390)
33. Peng S*, Liu XS, Wang T, Li Z, Zhou G, Luk KD, Guo XE, Lu WW. In vivo anabolic effect of strontium on trabecular bone was associated with increased osteoblastogenesis of bone marrow stromal cells. J Orthop Res 2010; 28:1208-1214. (IF: 3.102)
34. Peng S*, Zhang G, He Y, Wang X, Leung P, Leung K, Qin L. Epimedium-derived flavonoids promote osteoblastogenesis and suppress adipogenesis in bone marrow stromal cells while exerting an anabolic effect on osteoporotic bone. Bone 2009; 45:534-544. (IF: 4.626)
35. Zheng D*, Peng S*, Yang SH, Shao ZW, Yang C, Feng Y, Wu W, Zhen WX. The beneficial effect of Icariin on bone is diminished in osteoprotegerin-deficient mice. Bone. 2012 Apr 19; 51(1):85-92. (IF: 4.626)
36. Peng S*, Zhou G, Luk KD, Cheung KM, Li Z, Lam WM, Zhou Z, Lu WW. Strontium promotes osteogenic differentiation of mesenchymal stem cells through the Ras/MAPK signaling pathway. Cell Physiol Biochem 2009; 23:165-174. (IF: 5.14)
Publications as co-authors （n=21）
37. Lyu FJ, Peng S, Li J. Editorial: Progress on musculoskeletal disorders and stem cell therapies. Front Bioeng Biotechnol. 2023 Feb 23;11:1153525. (IF: 6.06)
38. Cui S, Zhou Z, Liu X, Richards RG, Alini M, Peng S, Liu S, Zou X, Li Z, Grad S. Identification and Characterization of Serum microRNAs as Biomarkers for Human Disc Degeneration: An RNA Sequencing Analysis. Diagnostics (Basel). 2020 Dec 8;10(12):1063. doi: 10.3390/diagnostics10121063.
39. Zhao B, Luo J, Wang Y, Zhou L, Che J, Wang F, Peng S, Zhang G, Shang P. Metformin Suppresses Self-Renewal Ability and Tumorigenicity of Osteosarcoma Stem Cells via Reactive Oxygen Species-Mediated Apoptosis and Autophagy. Oxid Med Cell Longev. 2019 Nov 18;2019:9290728. doi: 10.1155/2019/9290728. eCollection 2019.
40. Che J, Yang J, Zhao B, Zhang G, Wang L, Peng S, Shang P. The Effect of Abnormal Iron Metabolism on Osteoporosis. Biol Trace Elem Res. 2019 Aug 31. doi: 10.1007/s12011-019-01867-4.
41. Ning Z, Tan B, Chen B, Lau DSA, Wong TM, Sun T, Peng S, Li Z, Lu WW. Precisely Controlled Delivery of Abaloparatide through Injectable Hydrogel to Promote Bone Regeneration. Macromol Biosci. 2019 Jun;19(6):e1900020. doi: 10.1002/mabi.201900020.
42. Liang C, Li F, Wang L, Zhang ZK, Wang C, He B, Li J, Chen Z, Shaikh AB, Liu J, Wu X, Peng S, Dang L, Guo B, He X, Au DWT, Lu C, Zhu H, Zhang BT, Lu A, Zhang G. Tumor cell-targeted delivery of CRISPR/Cas9 by aptamer-functionalized lipopolymer for therapeutic genome editing of VEGFA in osteosarcoma. Biomaterials. 2017 Dec; 147:68-85. doi: 10.1016/j.biomaterials.2017.09.015.
43. Li J, Liang C, Zhang ZK, Pan X, Peng S, Lee WS, Lu A, Lin Z, Zhang G, Leung WN, Zhang BT. TAK1 inhibition attenuates both inflammation and fibrosis in experimental pneumoconiosis. Cell Discov. 2017 Jul 11;3:17023. doi: 10.1038/celldisc.2017.23. eCollection 2017.
44. Cui X, Huang C, Zhang M, Ruan C, Peng S, Li L, Liu W, Wang T, Li B, Huang W, Rahaman MN, Lu WW, Pan H. Enhanced osteointegration of poly(methylmethacrylate) bone cements by incorporating strontium-containing borate bioactive glass. J R Soc Interface. 2017 Jun;14(131). pii: 20161057. doi: 10.1098/rsif.2016.1057.
45. Liu J, Lu C, Wu X, Zhang Z, Li J, Guo B, Li D, Liang C, Dang L, Pan X, Peng S, Lu A, Zhang B, Zhang G. Targeting osteoblastic casein kinase-2 interacting protein-1 to enhance Smad-dependent BMP signaling and reverse bone formation reduction in glucocorticoid-induced osteoporosis. Sci Rep. 2017 Jan 27;7:41295. doi: 10.1038/srep41295.
46. Liu J, Liang C, Guo B, Wu X, Li D, Zhang Z, Zheng K, Dang L, He X, Lu C, Peng S, Pan X, Zhang BT, Lu A, Zhang G. Increased PLEKHO1 within osteoblasts suppresses Smad-dependent BMP signaling to inhibit bone formation during aging. Aging Cell. 2017 Apr;16(2):360-376. doi: 10.1111/acel.12566.
47. Liu J, Li D, Dang L, Liang C, Guo B, Lu C, He X, Cheung HY, He B, Liu B, Li F, Lu J, Wang L, Shaikh AB, Jiang F, Lu C, Peng S, Zhang Z, Zhang BT, Pan X, Xiao L, Lu A, Zhang G. Osteoclastic miR-214 targets TRAF3 to contribute to osteolytic bone metastasis of breast cancer. Sci Rep. 2017 Jan 10;7:40487. doi: 10.1038/srep40487.
48. Lv H, Jiang F, Guan D, Lu C, Guo B, Chan C, Peng S, Liu B, Guo W, Zhu H, Xu X, Lu A, Zhang G. Metabolomics and Its Application in the Development of Discovering Biomarkers for Osteoporosis Research. Int J Mol Sci. 2016 Dec 2;17(12). pii: E2018. Review.
49. Li D, Liu J, Guo B, Liang C, Dang L, Lu C, He X, Cheung HY, Xu L, Lu C, He B, Liu B, Shaikh AB, Li F, Wang L, Yang Z, Au DW, Peng S, Zhang Z, Zhang BT, Pan X, Qian A, Shang P, Xiao L, Jiang B, Wong CK, Xu J, Bian Z, Liang Z, Guo DA, Zhu H, Tan W, Lu A, Zhang G. Osteoclast-derived exosomal miR-214-3p inhibits osteoblastic bone formation. Nat Commun. 2016 Mar 7;7:10872. doi: 10.1038/ncomms10872.
50. Wang X, Guo B, Li Q, Peng J, Yang Z, Wang A, Li D, Hou Z, Lv K, Kan G, Cao H, Wu H, Song J, Pan X, Sun Q, Ling S, Li Y, Zhu M, Zhang P, Peng S, Xie X, Tang T, Hong A, Bian Z, Bai Y, Lu A, Li Y, He F, Zhang G, Li Y. miR-214 targets ATF4 to inhibit bone formation. Nat Med. 2013 Jan;19(1):93-100. doi: 10.1038/nm.3026.
51. He YX, Liu J, Guo B, Wang YX, Pan X, Li D, Tang T, Chen Y, Peng S, Bian Z, Liang Z, Zhang BT, Lu A, Zhang G. Src inhibitor reduces permeability without disturbing vascularization and prevents bone destruction in steroid-associated osteonecrotic lesions in rabbits. Sci Rep. 2015 Mar 9;5:8856. doi: 10.1038/srep08856.
52. Wang L, Zhang L, Pan H, Peng S, Lv M, Lu WW. Levels of neuropeptide Y in synovial fluid relate to pain in patients with knee osteoarthritis. BMC Musculoskelet Disord. 2014 Sep 27;15:319. doi: 10.1186/1471-2474-15-319.
53. Guo B, Zhang B, Zheng L, Tang T, Liu J, Wu H, Yang Z, Peng S, He X, Zhang H, Yue KK, He F, Zhang L, Qin L, Bian Z, Tan W, Liang Z, Lu A, Zhang G. Therapeutic RNA interference targeting CKIP-1 with a cross-species sequence to stimulate bone formation. Bone. 2014 Feb;59:76-88. doi: 10.1016/j.bone.2013.11.007.
54. Guo B, Peng S, Liang C, He X, Xiao C, Lu C, Jiang M, Zhao H, Lu A, Zhang G.
Recent developments in bone anabolic therapy for osteoporosis. Expert Rev Endocrinol Metab. 2012 Nov;7(6):677-685. doi: 10.1586/eem.12.63.
55. Huang S, Leung V, Peng S, Li L, Lu FJ, Wang T, Lu W, Cheung KM, Zhou G. Developmental definition of MSCs: new insights into pending questions. Cell Reprogram. 2011 Dec;13(6):465-72. doi: 10.1089/cell.2011.0045.
56. Li Z, Peng S, Pan H, Tang B, Lam RW, Lu WW. Microarchitecture and nanomechanical properties of trabecular bone after strontium administration in osteoporotic goats. Biol Trace Elem Res. 2012 Jan;145(1):39-46. doi: 10.1007/s12011-011-9158-y.
57. Shen Y, Liu W, Lin K, Pan H, Darvell BW, Peng S, Wen C, Deng L, Lu WW, Chang J. Interfacial pH: a critical factor for osteoporotic bone regeneration. Langmuir. 2011 Mar 15;27(6):2701-8. doi: 10.1021/la104876w.
主持和参与的科研项目
1. m6A甲基化修饰circStag1促进骨形成的作用及机制研究（主持人：彭松林；国自然面上项目；编号：82272488；年度：2023.1-2026.12；经费：52万）
2. Wnt及Notch信号通路在锶抑制骨吸收中的机制研究 (主持人；国自然面上项目；编号：81371989；年度：2014.1-2017.12；经费：70万)
3. Understanding the regulatory mechanism of microRNA-224 associated to the etiology of lumbar disc herniation （主持人；瑞士国际基金；编号：S-16-57P；年度：2016.1-2018.1；经费：9万瑞士法郎）
4. 深圳市运动系统组织与功能重建重点实验室（主持人；深圳市科技创新委；编号：ZDSYS20200811143752005; 经费：500万）
5. Wnt/β-catenin-OPG信号通路在Icariin调控骨代谢中的作用及机制研究 （主持人；广东省自然科学基金面上项目；编号：2015A030313776; 年度：2015.8-2018.8；经费：10万）
6. 含新型Smurf1抑制剂的海藻酸水凝胶对特定老年骨质疏松脊柱融合术中局部骨形成的影响研究（主持人；深圳市科技创新委深港创新圈项目；编号：SGLH20180625141602256; 年度：2019.10-2021.10；经费：200万）
7. 新型促进成骨微小RNA调控骨代谢及预防骨质疏松的作用及机制研究（主持人；深圳市科技创新委自由探索项目；编号：JCYJ20180305164659637; 年度：2019.3-2022.3；经费：50万）
8. 新型可注射促脊柱融合的海洋源壳聚糖水凝胶的研发（排名第二；深圳市科技创新委技术攻关项目；编号：JSGG20180504170427135; 年度：2019.3-2021.3；经费：160万/400万）
9. 海洋源生物活性骨水泥在脊柱压缩性骨折中应用的临床前研究（排名第二；深圳市科技创新委技术开发；项目；编号：CXZZ20150401152251209; 年度：2015.3-2017.3；经费：75万/150万）
10. 基于肠道菌群的无创骨质疏松标志物检测研究 （排名第二；深圳市科技创新委技术开发项目；编号：JCYJ20160229172757249；年度：2016.9-2019.9；经费：90万/300万）
11. 骨质疏松血清microRNA早期诊断技术研发（排名第二；深圳市科技创新委技术开发项目；编号：CXZZ20151015151249563；年度：2015.12-2017.12；经费：60万/150万）
12. microRNA在骨质疏松性椎体骨折中的作用和作为潜在生物标志的应用研究 （排名第二；广东省科技厅粤港合作项目；编号：2016A050503008；年度：2016.6-2019.6；经费：100万）
13. 骨保护素在淫羊藿苷调控骨代谢中的作用及机制研究 （主持人；深圳市科技创新委基础研究项目；编号：JCYJ20130402103240488；年度：2013.7-2015.7；经费：20万）
14. 中药小分子淫羊藿素治疗骨质疏松的作用及机理研究（排名第二；深圳市科技创新委基础研究项目；编号：JCYJ201416122812013；年度：2014.9-2016.9；经费：20万）
15. QCT 在骨质疏松症早期诊断及骨折风险评估的应用研究（排名第三；深圳市科技创新委国际合作项目；编号：GJHZ201416123146582；年度：2014.7-2016.7；经费：30万）
16. 淫羊藿素促进成骨的作用及机理研究（主持人；广东省自然科学基金；编号：JCYJ20130402103240488; 年度：2012-2014；经费：3万）
国家发明专利
1、专利名：一种天然多糖基可注射原位成型水凝胶及其制备方法和应用；专利号：ZL202010819581.7；专利发明人：彭松林、谭宝玉、陈欣、鲍志腾、唐榕泽、王尚；申请人：深圳市人民医院；申请日：2020.8.14；授权日：2022.6.17
2、专利名：一种可注射复合水凝胶及其制备方法和应用；专利号：ZL202010820028.5；专利发明人：陈欣、彭松林、谭宝玉、唐榕泽、鲍志腾、王尚；申请人：深圳市人民医院；申请日：2020.8.14；授权日：2022.6.17
3、专利名：一种骨软骨修复仿生材料及其制备方法和应用；专利号：ZL202010871881.X；专利发明人：彭松林、贺小琴、赵津、何同忠、王尚；申请人：深圳市人民医院；申请日：2020.8.26；授权日：2022.8.09
4、专利名：一种MBMP2蛋白复合水凝胶及其制备方法和应用；专利号：ZL202110990729.8；专利发明人：彭松林、陈欣、谭宝玉、唐榕泽、杨大志；申请人：深圳市人民医院；申请日：2021.8.26；授权日：2022.7.29
5、专利名：一种骨质疏松诊断标志物及其应用；专利号：ZL202011561140.8；专利发明人：彭松林、何同忠、谭宝玉、陈高扬、王尚、贺小琴；申请人：深圳市人民医院；申请日：2020.12.25；授权日：2022.7.05
6、专利名：一种促骨再生复合材料及其制备方法；专利号：ZL202010914619.9；专利发明人：彭松林、何同忠、谭宝玉、陈高扬、王尚、贺小琴；申请人：深圳市人民医院；申请日：2020.09.03；授权日：2022.7.15
7、专利名：一种可注射水凝胶及其制备方法和应用；专利号：ZL202110552066.1；专利发明人：彭松林、谭宝玉、陈欣、唐榕泽、杨大志；申请人：深圳市人民医院；申请日：2021.05.20；授权日：2023.1.13
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